Researchers assess whether drones can spray pesticides better than conventional technologies in terms of cost, capacity, and management efficiency

Drones could soon be adopted as essential tools for various agricultural tasks; however, with respect to their use in farm management, research is still lacking. To address this issue, researchers in Japan compared drones to well-established technologies for spraying pesticide over rice paddy fields. Using statistical data, the researchers explore both advantages and limitations of drones and whether they currently offer an edge regarding costs, capacity, and management efficiency.

Can pesticide use in rice paddy fields be made smarter?
Can pesticide use in rice paddy fields be made smarter?
Can unmanned aerial vehicles be used for pesticide use in an efficient manner? In a new study, researchers assessed their use in rice paddy fields, in terms of costs, capacity, and management efficiency

Besides enabling more potent smartphones and higher download speeds while riding the…


Scientists develop biofuel cells that can power wearable electronics purely by using human sweat

Wearable electronic devices and biosensors are great tools for health monitoring, but it has been difficult to find convenient power sources for them. Now, a group of scientists from Japan has successfully developed and tested a wearable biofuel cell array that generates electric power from the lactate in the wearer’s sweat, opening doors to electronic health monitoring powered by nothing but bodily fluids.

It cannot be denied that, over the past few decades, the miniaturization of electronic devices has taken huge strides. Today, after pocket-size…


Anti-cancer drug delivery to target tumor sites now becomes more effective with novel multi-stimuli-responsive drug delivery systems

Hydrogels are often used as drug delivery systems, but to be effective carriers for anti-cancer drugs, they need to be responsive to varied stimuli in the tumor microenvironment. Now, scientists from Japan have developed novel hydrogels to effectively deliver drugs to tumor sites in response to temperature and pH changes in the tumor microenvironment. These multi-stimuli-responsive hydrogels can eliminate remnant cancer cells following tumor excision through controlled drug release, offering hope for effective cancer treatment.

Anti-cancer drug delivery to target tumor sites now becomes more effective with novel multi-stimuli-responsive drug delivery systems

Cancer therapy in recent times relies on the…


A noninvasive method for quantifying fat content in liver can aid medical research and diagnosis of liver diseases

Excessive fat accumulation in the liver can lead to serious medical problems, including liver failure. Thus, understanding the distribution of lipids within the liver is a critical step in diagnosing fatty liver diseases. A team of researchers at Tokyo University of Science has now shown that near-infrared hyperspectral imaging permits the visualization of lipid content in mouse liver. This technique can facilitate the diagnosis of fatty liver diseases in medical research.

Scientists at Tokyo University of Science, Japan, have now showed that near-infrared hyperspectral imaging is an effective method for the quantitative visualization of lipid content in mouse liver.
Scientists at Tokyo University of Science, Japan, have now showed that near-infrared hyperspectral imaging is an effective method for the quantitative visualization of lipid content in mouse liver.
Scientists at Tokyo University of Science, Japan, have now showed that near-infrared hyperspectral imaging is an effective method for the quantitative visualization of lipid content in mouse liver.

Nonalcoholic fatty liver disease (NAFLD) is a pathological condition characterized by…


Scientists show how a receptor protein plays a role in the immune response, yielding a potential therapeutic target for diseases like rheumatoid arthritis

TARM1 is a receptor protein whose role in the functioning of the immune system is unknown. In a new study, scientists from Japan have explored the potential role of TARM1 in the pathogenesis of rheumatoid arthritis by analyzing mouse models. They found that TARM1 activated dendritic cells, and development of collagen-induced arthritis (CIA) was notably suppressed in TARM1-deficient mice and by treatment with TARM1-inhibitory soluble TARM1 proteins. This makes the protein a potential therapeutic target.

Autoimmune…


Scientists report on the structural and molecular factors governing the stability of a protein complex involved in DNA repair pathways in cells

The cells in our body are constantly fighting off the threat of cancer by repairing damaged DNA. In a new study, scientists from Tokyo University of Science investigate the structure of an elusive protein complex that plays a key role in the activation of the “Fanconi anemia pathway” involved in DNA repair, and report on the factors governing its stability. Their insights can potentially help find novel treatments disorders involving chromosomal instability, including cancer.

Dissociation of the FANCM-MHF complex: After X-ray crystallography (XRC), scientists found that tetrahedral and needle-shaped forms of recombinant FANCM-MHF complex contained only MHF without FANCM. Upon biochemical analysis, they found that this was due to the organic solvent used in sample preparation for XRC and exposure to oxidizing conditions. | Image credit: Tatsuya Nishino from Tokyo University of Science

One of the most…


New study shows that stroke byproduct acrolein activates the precursor of heparanase, an enzyme that degrades the glycocalyx in the blood-brain barrier

The blood–brain barrier prevents immune cells from circulating freely in the brain, and the breakdown of its function is a major cause of post-stroke inflammation. Now, for the first time, researchers have identified how a toxic stroke byproduct, acrolein, could activate the barrier-degrading enzyme proheparanase (proHPSE). The research group has discovered that proHPSE degrades the glycocalyx within the post-stroke brain’s blood vessels, providing hope for new and effective therapeutics against post-stroke inflammation.

Scientists from Japan and the United States have identified a new mechanism of blood–brain barrier degradation in the post-stroke brain, involving acrolein-induced modifications of proheparanase. This discovery could lead to the production of newer and more effective drugs for stroke-related disorders | Photo courtesy: toubibe from Pixabay

Strokes are a leading cause of…


Scientists develop new biosensing device to chemically monitor the state of muscles during physical exercise

Lactate, a compound present in sweat, is an important biomarker to quantify during exercise. However, available wearable sensors can cause skin irritation, which calls for the use of different materials. In a recent study, scientists at Tokyo University of Science have developed a soft and nonirritating microfluidic sensor for the real-time measurement of lactate concentration in sweat. This wearable device will help monitor the state of the body during intense physical exercise or work.

It’s important to use non-irritating materials in the design of wearable sensors that are used for quantifying lactate levels during exercise | Photo courtesy: Ketut Subiyanto on Pexels

With the seemingly unstoppable advancement in the fields of miniaturization and…


How “elicitors” can initiate defense responses in plants against herbivores, and can potentially lead to development of pesticide-free agriculture

Plants are known to possess solid immune response mechanisms. One such response is “sensing” attack by herbivorous animals. In a new review article, Prof. Arimura from Tokyo University of Science, Japan, discusses “elicitors” — the molecules that initiate plant defense mechanisms against herbivore attack. He highlights the major types of elicitors and the underlying cellular signaling, and states that this could spur research on organic farming practices that could prevent the use of harmful pesticides.

How “elicitors” can initiate defense responses in plants against herbivores, and can potentially lead to development of pesticide-free agriculture
How “elicitors” can initiate defense responses in plants against herbivores, and can potentially lead to development of pesticide-free agriculture
How “elicitors” can initiate defense responses in plants against herbivores, and can potentially lead to development of pesticide-free agriculture

Nature has its way of maintaining…


Scientists reveal peculiar surface structure in materials resembling quasicrystals with interesting implications for its magnetic properties

Ever since their discovery, quasicrystals have garnered much attention due to their strange structure. Today, they remain far from being well-understood. In a new study, scientists reveal, for the first time, a unique shifting surface atomic structure in a material emulating quasicrystals, opening doors to the better understanding of magnetic and superconducting properties of quasicrystals, and potential applications in semiconductor film growth.

The Tsai-type clusters one inside another of the Au-Al-Tb approximant the scientists chose (a), and the corresponding spin
The Tsai-type clusters one inside another of the Au-Al-Tb approximant the scientists chose (a), and the corresponding spin
The Tsai-type clusters one inside another of the Au-Al-Tb approximant the scientists chose (a), and the corresponding spin icosahedra (b). | Photo courtesy: Ryuji Tamura of Tokyo University of Science

Between chemistry classes, gemstones, and electronics, the idea of crystals, substances with an ordered and periodic arrangement of atoms is quite common…

Tokyo University of Science

Tokyo University of Science (TUS) is one of the most well-known, respected, and the largest science-specialized private research universities in Japan.

Get the Medium app

A button that says 'Download on the App Store', and if clicked it will lead you to the iOS App store
A button that says 'Get it on, Google Play', and if clicked it will lead you to the Google Play store